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It is good to see any cluster randomised
2019-05-06
It is good to see any cluster-randomised DMOG trial of a handwashing intervention, much more a successful one. Globally there is considerable funding invested in handwashing promotion, yet the kind of rigorous study published in this month\'s issue of by Adam Biran and colleagues is rare in the li
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Modelling studies have estimated that the
2019-05-06
Modelling studies have estimated that the implementation of Xpert MTB/RIF, either in addition to or as a replacement to smear microscopy, will be cost-effective for the diagnosis of tuberculosis and mutidrug-resistant (MDR) tuberculosis in countries with a high burden. The incremental cost of each d
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br Hacia un monote smo ta no
2019-05-05
Hacia un monoteísmo taíno Debido al hecho de que la irreductible diversidad de los cemíes parece demasiado peligrosa para ser comparada con la noción antigua de divinidad, la Relación trata de proponer, aunque de manera discreta, otra forma de interpretación: es decir, la búsqueda de las huellas
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We also thank Kate Mandeville and Adamson Muula for
2019-05-05
We also thank Kate Mandeville and Adamson Muula for their letter and agree with the need to ensure resources are available to fund salaries for newly trained doctors and other health workers to allow these workers to be absorbed into the under-resourced Malawian health system. The doctors\' salary c
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Surgical intervention remains obligatory for
2019-05-05
Surgical intervention remains obligatory for hemodynamic instability, including shock secondary to renal bleeding, complex lacerations, renal pelvic, or ureteral injury, plus certain renovascular conditions. The prolonged warm ischemia that may occur when under renal neoplasty usually results in irr
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br Materials and methods br Results
2019-05-05
Materials and methods Results Discussion To our best knowledge, a multi-modality approach to systematically characterize an OS in vivo orthotopic model, using an aggressive OS cell line has not been previously reported. The advantage of using multi-modality approach i.e. BLI, histopathology
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br Material and methods br Results Thirty
2019-05-05
Material and methods Results Thirty-one patients were enrolled consecutively, in this randomized study, between January 2010 and March 2012. The mean age was 65.5±13.7 years. The proportion of patients with primary prevention indication was 25.8% and ischemic cardiomyopathy was 29.0%. All repo
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Early repolarization ER is characterized by elevation of
2019-05-05
Early repolarization (ER) is characterized by elevation of the QRS-ST junction (J point) and QRS notching or slurring (J wave) in multiple leads, especially the inferior and/or left precordial leads. Although this finding has been considered to be a benign ECG manifestation, Haïssaguerre et al repor
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La relaci n entre el narcotr fico y los grupos
2019-05-05
La relación entre el narcotráfico y los grupos guerrilleros y los paramilitares se ha dado: “[…] no sólo como fuente de financiación sino como actor con intereses propios, ya que han aumentado significativamente las ‘familias’ que se dedican al tráfico de drogas, que a su vez están aumentando sus fo
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br To see how the quantity of osteosarcoma in vitro
2019-05-04
To see how the quantity of osteosarcoma in vitro studies developed overtime, we set out to systematically identify all the drugs that have been tested on osteosarcoma hydroxypropyl beta cyclodextrin in vitro in the past two decades. A PubMed search strategy was compiled which can be found in Supp
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Cardiac fibroblasts express various ion channels in
2019-05-04
Cardiac fibroblasts express various ion channels, in particular voltage-gated K dopamine receptor and nonselective cation channels of the transient receptor potential (TRP) family . Both K and TRP channels are important determinants of fibroblast function, with TRP channels acting as Ca entry pathw
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The canonical or catenin dependent Wnt signaling pathway
2019-05-04
The canonical, or β-catenin dependent, Wnt signaling pathway is critical for the regulation of osteoblast proliferation and survival [95]. Soluble inhibitors of the canonical Wnt pathway such as Dickkopf (DKK1), produced by OBL, and sclerostin, from osteocytes, play important roles in the regulation
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During the ACh provocation test our
2019-05-04
During the ACh provocation test, our patient did not complain of chest pain, ECG showed no discernible ST-T changes, and CAG demonstrated no spastic findings. These indicate that ACh evoked the J wave by its direct pharmacological actions in this case. J waves are currently recognized as a surface E
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Significant uncertainty remains about the precise vectors th
2019-05-04
Significant uncertainty remains about the precise vectors, the plasticity of vector host-selection (ie, monkey human) and the exact location of vector exposure that results in human transmission of especially across different parts of Asia. In particular, uncertainty exists as to whether transmiss
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br Discussion Primary lymphoma of bone is a rare
2019-04-30
Discussion Primary lymphoma of bone is a rare disease, first described by Oberling in 1928 and he labeled it as reticulum cell sarcoma of bone because of the presence of characteristic reticulin fibers within the lesion [5]. This work was followed by Parker and Jackson and later by Ivin and Bosto
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