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br Conflict of interest br Introduction Hepatosplenic T
2019-05-28
Conflict of interest Introduction Hepatosplenic T cell lymphoma (HSTCL) is a very rare type of hematologic malignancy, making up about 5% of peripheral T-cell lymphomas. It predominantly affects young male adults, with a higher incidence in patients submitted to immunosuppressive treatment for
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Recently a reciprocal fusion between YPEL yippee
2019-05-28
Recently, a reciprocal fusion between YPEL5 (yippee-like 5) and PPP1CB (serine/threonine protein phosphatase-1 beta catalytic subunit) was described to be exclusively expressed in more than 90% of primary CLL samples [5] and not in control samples or samples from patients with other hematological ma
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br Conflict of interest br Introduction The use
2019-05-28
Conflict of interest Introduction The use of implantable defibrillation devices such as an implantable cardioverter–defibrillator (ICD) or a cardiac resynchronization therapy device with a defibrillator (CRT-D) is the primary therapy for improving prognoses of patients with life-threatening ve
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br Conclusions br Disclosures br Introduction Since their in
2019-05-28
Conclusions Disclosures Introduction Since their introduction, at the end of fifties, cardiovascular implantable devices (CIEDs) have widely expanded in number and in their functions [1,2]. The dramatic increase in the number of CIEDs implanted in the last decade is mainly due to the aging
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CT analysis of tumour bearing bones showed significantly
2019-05-28
μCT analysis of tumour bearing bones showed significantly increased bone density in animals receiving zoledronic acid, alone or in combination with doxorubicin, compared to PBS control. Our results confirmed that a single dose of zoledronic pde inhibitor caused sustained bone effects throughout the
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br D microCT data Bone
2019-05-28
3D microCT data Bone volume (BV/TV) ranged from 10.8 to 13.5% consistent with the published literature [18]. Trabecular thickness (Tb.Th), trabecular Yeast Extract (Tb.Sp), trabecular number (Tb.N) and bone surface per tissue area (BS/TV) values were also consistent with the range published in t
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br Conflict of interest br Introduction Patients with
2019-05-28
Conflict of interest Introduction Patients with structural heart disease have an increased risk of sudden cardiac death, secondary to ventricular tachyarrhythmias in most cases. Implantable cardioverter–defibrillators (ICDs) are the treatment of choice. However, ventricular tachyarrhythmias ca
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In addition we demonstrated that the combination
2019-05-27
In addition, we demonstrated that the combination of PCBP2 siRNA and LY2109761 had a potent silencing effect on collagen expression (Fig. 8). Both HSC-T6 myd88 signaling and primary HSCs were used to evaluate the combinational treatment. LY2109761, a TGFβ receptor type I/II kinase inhibitor, has be
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El poeta becario no es la nica figura que impacta
2019-05-27
El poeta becario no es la única figura que impacta KPT-185 cost esta generación; hay otra menos visible, pero que sin duda resulta también relevante para un campo como la poesía, de escaso interés comercial. En los espacios alternativos que no participan de la normativa burocrática, se crean figuras
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At the mechanistic level our results strongly suggested that
2019-05-27
At the mechanistic level, our results strongly suggested that the cholestatic protective effect of STS was most likely accounted for by the activation of LXR, a nuclear receptor known for its anti-cholestatic activity. The activation of LXR was supported by the induction of typical LXR target genes,
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br zoonoses are responsible for a staggering
2019-05-27
13 zoonoses are responsible for a staggering 2·2 billion human illnesses and 2·3 million deaths per year, mostly in low-income and middle-income countries () where the correlation between rates of protein malnutrition and incidence of endemic zoonotic diseases is 99%. Veterinary medicine has an i
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br Control of visceral leishmaniasis requires access to low
2019-05-27
Control of visceral leishmaniasis requires access to low-cost, safe, and effective treatment. Amphotericin causes infusion-related fever, rigor, and nephrotoxicity, limiting its use. Ambisome—a liposomal amphotericin manufactured by Gilead—is better tolerated and is effective as a single dose. How
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El otro paradigma cuyo alcance y magnitud exige atenci
2019-05-27
El otro paradigma cuyo alcance y magnitud exige atención particular es la deconstrucción y todo el giro lingüístico que la precede, un enfoque en muchos sentidos inverso death associated protein kinase la colonialidad, aunque no en todos. Sus cauces precursores en América Latina podrían partir de fi
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Contrario a lo que concluye Guajardo en torno a
2019-05-27
Contrario bcl-xl inhibitor lo que concluye Guajardo, en torno a que la privatización dejó de lado el tema central de la reforma del Estado y de las nuevas capacidades públicas, de ahí que los efectos de décadas de reformas económicas sean todavía confusos e inconsistentes, el fenómeno globalizador s
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Esto es visible no s lo en las notas
2019-05-27
Esto es visible no sólo en las notas necrológicas, sino también en los discursos que homenajean ambroxol hydrochloride alguien en ocasión de su retiro o jubilación. En ellos encontramos rasgos comunes con las notas necrológicas, sobre todo en la idea de una herencia que deja el que se va, y que cons
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