• Introduction Acute acalculous cholecystitis ACC is defined a

  2019-06-19

  

  Introduction Acute acalculous cholecystitis (ACC) is defined as an acute necroinflammatory disease of the gallbladder in the absence of cholelithiasis and has a multifactorial pathogenesis [1]. ACC has very rarely been described in patients undergoing myelosuppressive chemotherapy for acute myelobl

• People in LMICs are disproportionately

  2019-06-19

  

  People in LMICs are disproportionately exposed to severe acute kidney injury and have substantially less access to effective treatment than do people in higher-income countries. Framing acute kidney injury as a driver of substantial inequity in disease risk and mortality in low-resource countries, t

• scd1 Introduction The World health organization WHO defines

  2019-06-18

  

  Introduction The 2008 World health organization (WHO) defines acute leukemias with ambiguous lineage (ALAL) as those leukemias which show no clear differentiation towards either myeloid or lymphoid lineage. It includes acute undifferentiated leukemias which express no specific markers for both line

• I received a grant from The Kendeda

  2019-06-18

  

  I received a grant from The Kendeda Fund to write and promote my book, , on which this comment is based. I thank Richard King (Chatham House, London, UK) for data assistance, Christian Guthier (All is Possible, Oxford, UK) for graphic design, and Sarah Cornell (Stockholm Resilience Centre, Stockholm

• But consider the alternative outcomes of so

  2019-06-18

  

  But consider the alternative outcomes of so-called virtuous plate-clearing. If the additional portion does not displace other consumption—ie, the amount eaten subsequently is not reduced—then total consumption will have increased. A lack of displacement means no reduction in demand for agricultural

• However she had an attack on Day

  2019-06-18

  

  However, she had an attack on Day 7. The ECG monitor was normal until 4:25 AM (Fig. 1a). ST segment elevation was evident, and the patient experienced chest pain at 4:30 AM (Fig. 1b). ST segment elevations were seen in leads II, III, and aVF on the 12-lead ECG. As sublingual nitroglycerin was ineffe

• br Conflict of interest br Introduction Idiopathic left vent

  2019-06-18

  

  Conflict of interest Introduction Idiopathic left ventricular tachycardia (ILVT) with a right bundle-branch block (RBBB) configuration and superior or left axis is a distinct entity that arises in the left ventricle, mostly because of a reentry mechanism and is usually verapamil sensitive [1–6

• br ECM cancer and metastasis For cells

  2019-06-18

  

  ECM, cancer and metastasis For hcv virus to become cancerous they must acquire the ability to survive, grow and invade leading to malignant transformation, tumour formation and ultimately overt secondary metastasis. Abnormal ECM can promote these abilities and is a well-documented hallmark of ca

• Enasidenib br Conflict of interest br Introduction Catheter

  2019-06-18

  

  Conflict of interest Introduction Catheter ablation is an effective approach for the management of patients with atrial fibrillation (AF) [1–7]. Pulmonary vein isolation (PVI) is one of the most common strategies of AF ablation, but the outcome of PVI alone for patients with persistent AF is p

• Common and rare SCN A variants may contribute

  2019-06-18

  

  Common and rare SCN10A variants may contribute to AF susceptibility [59,60]. SCN10A mutations (R14L and R1268Q) cause a loss of function of Nav1.5 current, which is expected to reduce excitability and lead to the development of the arrhythmogenic substrate responsible for BrS and AF. A common varian

• This relationship will be complicated the prevalence of

  2019-06-18

  

  This relationship will be complicated: the prevalence of malaria infection in non-pregnant adults is lower than that for children within the same setting, a finding probably related to the differing levels of immunity in the adult and child populations. Since immunity depends on previous exposure an

• But consider the alternative outcomes of so called virtuous

  2019-06-18

  

  But consider the alternative outcomes of so-called virtuous plate-clearing. If the additional portion does not displace other consumption—ie, the amount eaten subsequently is not reduced—then total consumption will have increased. A lack of displacement means no reduction in demand for agricultural

• br Discussion We evaluated and determined the incidence

  2019-06-17

  

  Discussion We evaluated and determined the incidence and severity of subjective reports of dyspepsia symptoms due to dabigatran. Based on the results of the RE-LY trial [4], the AE that was significantly more common with dabigatran than with warfarin was dyspepsia. In the sub-group (326 Japanese

• The authors of the NCCN non small cell

  2019-06-17

  

  The authors of the NCCN non-small cell lung cancer guidelines provide the most guidance about radiotherapy dosing for painful bone metastases of any of the primary sites evaluated [39]. Bone metastases due to non-small cell lung cancer are separated into those “with soft tissue mass” versus those “w

• br Discussion Implantation of a defibrillation patch under t

  2019-06-17

  

  Discussion Implantation of a defibrillation patch under thoracotomy has been used for implantation in the beginning and is still in use in cases where venous access is inadequate, and studies have reported postoperative Swainsonine failure in 3 of 35 ICD patients treated with a defibrillation pat

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