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K02288 G DH has gained interest because
2020-08-05
G3DH has gained interest because of its broad substrate specificity and site-selective oxidation properties [9,10]. The conversion product, 3-ketoglycoside, possesses potential as a starting material for the chemical industry such as in polymer and surfactants because the keto group becomes a specif
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It is outside the scope of this review to discuss
2020-08-05
It is outside the scope of this review to discuss all members of the Ca2+-signaling toolkit involved in the modulation of autophagy and we will focus here only on those that are necessary for the topic of this review (see Section 5), i.e. CaM, the inositol 1,4,5-trisphosphate (IP3) receptor (IP3R) a
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br Funding This work was supported
2020-08-05
Funding This work was supported by a research grant of the Deutsche Forschungsgemeinschaft (SCHN477-9-2 to R.S.S), the Manfred-Stolte-Stiftung (to R.S.S.) and by a research grant from the German Cancer Aid (Deutsche Krebshilfe, No. 106696/TP 5 to T.F.). Introduction Death-associated protein k
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br Author contributions br Acknowledgments This
2020-08-05
Author contributions Acknowledgments This work was supported by the Polish National Science Center grant SONATA [2012/07/D/NZ4/00814] and by the Ministry of Sciences and Higher Education [556/MOB/2009/0]. Introduction Oral contraceptives (OCs) are one of the most widely used drugs by women
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The COMT gene is involved in numerous psychological and phys
2020-08-05
The COMT gene is involved in numerous psychological and physiologic processes, including modulation of pain. Polymorphisms in this gene have also been associated with many painful conditions, including pain sensitivity in children. Bivariate analysis demonstrated that individuals with heterozygous C
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ZM 306416 br Model of receptor binding and
2020-08-05
Model of receptor binding and activation It has been proposed that ETAs display an inactive conformation (R) or an active conformation (R*) that can bind one or more G proteins (G) and other ZM 306416 proteins (Figure 1a). An orthosteric agonist (e.g. ET1) binds sequentially and polyvalently to R
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Arkansas supplies about of the annual rice production in the
2020-08-05
Arkansas supplies about 48% of the annual rice production in the U.S. Riceland Foods Inc., the world’s largest rice milling industry in Arkansas, produces about 125 millions of bushels of paddy (rice before threshing) on yearly basis [10]. This large amount of paddy yields a significant quantity of
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Acknowledgements We thank the University of Hull for funding
2020-08-04
Acknowledgements We thank the University of Hull for funding, BBSRC for support (GM), and the EPSRC National Mass Spectrometry Service (Swansea) for accurate mass determination of 2e and 3e. Introduction Mitochondria are vital organelles for most eukaryotic cells (Karnkowska et al., 2016). They
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In summary our findings show that LPS
2020-08-04
In summary, our findings show that LPS can activate CysLT2R on microglial 4-iodo-SAHA to induce microglial inflammation and microglia-dependent neuronal death. Furthermore, pharmacological inhibition or knocking down of CysLT2R expression protects neurons against neurotoxicity via suppression of LPS
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In agreement with our results showing the presence of CysLT
2020-08-04
In agreement with our results showing the presence of CysLT2 receptors in alveolar leukocytes, both CysLT1 and CysLT2 receptors have been reported to be expressed not only in macrophages, but also in eosinophils,19, 21 mast cells, basophils, and dendritic cells. The functional importance of CysLT2 r
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Resource constrained small satellites need
2020-08-04
Resource constrained small satellites need to detect more CFEs with less time and memory, so neither the error detection rate nor time and memory overhead involved alone can reflect the effectiveness of the CFC techniques. We employ an evaluation factor to evaluate the entire effectiveness of the CF
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The aim of our study was to understand the
2020-08-04
The aim of our study was to understand the role of serum ChE activity in patients with radiation-recurrent CaP who underwent SRP. To this end, we evaluated the association of preoperative serum ChE with clinicopathologic characteristics and outcomes in patients treated with SRP for biochemically rec
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br Methods br Discussion In a recent
2020-08-04
Methods Discussion In a recent survey among 2625 high risk patients on atorvastatin, 10.5% of patients achieved an LDL-target of by their physicians to have clinically met the target [20]. Similarly, the data from DYSIS II showed that use of lipid lowering therapy was widespread and improved
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Caspase-1, human recombinant proteinase australia In this in
2020-08-04
In this instance the actual limits to specificity are nearly impossible to estimate a priori. Figure 1C examines a practical case, considering how Caspase-1, human recombinant proteinase australia that act on a linear substrate discriminate against a competitor metabolite containing one additional
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Guanfacine hydrochloride Proteolysis in ensiled forage resul
2020-08-04
Proteolysis in ensiled forage results mainly from plant proteolytic enzymes (Ohshima and McDonald, 1978, McKersie, 1981, Heron et al., 1988). McKersie (1981) demonstrated the presence of at least three proteolytic enzymes in Lucerne (i.e., carboxypeptidase, aminopeptidase, Guanfacine hydrochloride
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