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fccp australia br Materials and methods br Results
2022-06-18

Materials and methods Results We examined the cardiac mitochondrial density of HKI and markers of oxidative and metabolic stress in trout exposed to an aerated control exposure, an aerated (normoxic) thermal insult, or a hyperoxic thermal insult. Should mtHK provide a cardioprotective effect i
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Curcumin is a major yellow
2022-06-18

Curcumin is a major yellow pigment in turmeric ground rhizome of Curcuma longa Linn, which is used widely as a spice and coloring agent in several foods such as curry, mustard and potato chips as well as cosmetics and drugs (Okada et al., 2001, Joe et al., 2004). Curcumin represents a class of anti-
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Concerning the molecular mechanisms underlying transcription
2022-06-18

Concerning the molecular mechanisms underlying transcriptional regulation of the GSTP1-1 gene expression we and others have characterized structural and functional properties of the human GSTP1-1 promoter. GSTP1-1 gene promoter activity is driven by a TATA-box [16] as well as Spl [16], [17], AP-1 [1
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Strengths The primary feature of GPR agonists
2022-06-17

Strengths The primary feature of GPR119 agonists resides in their dual mechanism of action in regulating blood glucose 1, 2, 3, 15. GPR119 agonists stimulate GLP-1 release from intestinal L AZD0156 as well as glucose-dependent insulin secretion and insulin promoter activity enhancement in pancreati
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The effects of opioids such as
2022-06-17

The effects of opioids such as morphine are mediated through the opioid receptors. Opioid receptors are widely expressed both peripherally and in the CNS (Chen et al., 1993, Evans et al., 1992). The opioid agonist morphine has been shown to amplify the effect of the tubular cell-gp120 interaction on
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Previous studies showed that pregnancy rate improves when ew
2022-06-17

Previous studies showed that pregnancy rate improves when ewes have a BCS that exceeds a minimum threshold [43]. The pregnancy rate is increased in sheep with BCS ≥2.5 [44] and >2 [45]. In this work, pregnancy rate was higher in the GnRH group with low BCS compared to the hCG and Control groups. Des
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ICH induced striatal lesion produced a reduction
2022-06-17

ICH-induced striatal lesion produced a reduction of EAAT1 expression analogous to the decreased glutamate uptake at 6 h. The combined reduction of excitatory amino toll like receptors transporters and of glutamate uptake activity might explain the well-known glutamate excitotoxicity following brain
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In our study we observed elevation of the fluorescent intens
2022-06-17

In our study, we observed elevation of the fluorescent intensity in the layers without synaptic contacts (OS, ONL, INL, and GCL). In the enzyme-linked fluorescence assay system, released glutamate is catalyzed by the enzyme on the surface of a quartz glass. Therefore, the diffusion of glutamate onto
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Polyunsaturated fatty acids PUFAs represent a class
2022-06-17

Polyunsaturated fatty acids (PUFAs) represent a class of lipids that contain two or more carbon double (unsaturated) bonds (CC) and classified as n-3, n-6 and n-9 fatty acids. PUFAs including n-3 such as docosahexaenoic renin inhibitor (DHA), eicosapentaenoic acid (EPA) and n-6 such as arachidonic a
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Assuming thus a positive signal for both GLUT and GLUT
2022-06-17

Assuming thus a positive signal for both GLUT1 and GLUT3 in our conditions, a more detailed explanation of the results observed through immunocytochemistry is needed. In this way, it must be reminded that syncytiotrophoblasts compose the outer layer of the trophoblast, are in direct contact with mat
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LbGlcK crystallized as a ligandless dimer in
2022-06-17

LbGlcK crystallized as a ligandless dimer in the asymmetric unit of space group P21 (Fig. 1a) with two identical subunits stabilized by a large contact surface area of 2295 Å2 (13% of the total surface area) as determined by the Protein Interfaces, Surfaces, and Assemblies (PISA) server [18]. Each m
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Various strategies have been pursued in
2022-06-17

Various strategies have been pursued in the search for GIPR antagonists. Antibodies raised against both GIP(1–42) [14], [15] or the GIPR [16], [17], a small molecule antagonist [18], amino alpha adrenergic blockers substitutions of GIP(1–42) [19], and various GIP(1–42) truncations and modifications
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br GJs in the brain br Alterations of GJs
2022-06-17

GJs in the brain Alterations of GJs in epilepsy The role of GJ blockers and openers in epilepsy As previously known, GJ-mediated electrical coupling plays a role in the generation of highly synchronous electrical activity. The hypersynchronous neuronal activity is a significant feature of
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So far several methods have been used
2022-06-17

So far, several methods have been used to monitor the level of GJC and its regulation in astrocytes studied in acute keap1 nrf2 slices (see Giaume et al., 2012). This mainly includes approaches based either on electrophysiological properties of gap junction channels or on “dye coupling” experiments
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br Materials and method http www apexbt com media
2022-06-17

Materials and methods Results Discussion This study provide for the first time a report on GALP in fish, providing new information towards the distribution and functional characterization of the galaninergic system in these vertebrates. Our studies show the detailed neuroanatomical distribu
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